diff --git a/docs/changelog.md b/docs/changelog.md
index c90427e0..bafb472e 100644
--- a/docs/changelog.md
+++ b/docs/changelog.md
@@ -6,6 +6,9 @@ Requires libvips v8.12.2
 
 ### v0.30.1 - TBD
 
+* Allow use of `toBuffer` and `toFile` on the same instance.
+  [#3044](https://github.com/lovell/sharp/issues/3044)
+
 * Skip shrink-on-load for known libjpeg rounding errors.
   [#3066](https://github.com/lovell/sharp/issues/3066)
 
diff --git a/lib/output.js b/lib/output.js
index 28d6b5a8..c4a23429 100644
--- a/lib/output.js
+++ b/lib/output.js
@@ -139,6 +139,7 @@ function toBuffer (options, callback) {
   } else if (this.options.resolveWithObject) {
     this.options.resolveWithObject = false;
   }
+  this.options.fileOut = '';
   return this._pipeline(is.fn(options) ? options : callback);
 }
 
diff --git a/test/unit/io.js b/test/unit/io.js
index 258b42b4..67c0f246 100644
--- a/test/unit/io.js
+++ b/test/unit/io.js
@@ -328,6 +328,20 @@ describe('Input/output', function () {
       });
   });
 
+  it('Allow use of toBuffer and toFile with same instance', async () => {
+    const instance = sharp({
+      create: {
+        width: 8,
+        height: 8,
+        channels: 3,
+        background: 'red'
+      }
+    });
+    await instance.toFile(fixtures.path('output.jpg'));
+    const data = await instance.toBuffer();
+    assert.strictEqual(Buffer.isBuffer(data), true);
+  });
+
   it('Fail when output File is input File', function (done) {
     sharp(fixtures.inputJpg).toFile(fixtures.inputJpg, function (err) {
       assert(err instanceof Error);